Antiulcer activity of aqueous extracts of Annona squamosa seed extract was studied in Rats by pyloric ligation method. The extract at dose of 100,200 mg/kg produced significant inhibition of gastric lesion induced by Pylorus ligation induced ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, PH, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P<0.001) decreases the volume of gastric acid secretion, PH, free acidity, total acidity and ulcer index with respect to control.
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